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Hair loss is a concern some patients raise

If you have sub-optimal levels with symptoms, its worth a trial of B12 even if your serum B12 levels are normal

High-quality human clinical trials are lacking, and optimal dosing, long-term safety, and efficacy have not been established, meaning its use for IBS and Crohns should be considered investigational rather than a standard therapeutic option

This rare condition can lead to: low plasma carnitine progressive cardiomyopathy, or heart muscle disease skeletal myopathy hypoglycemia hypoammonemia weak muscles in the hips, shoulders upper arms, legs, neck, and jaw muscles Untreated it is fatal